Testosterone and Mood: Understanding How Low T Affects Men’s Mental Health

Many men notice changes as they get older — less energy, more irritability, or a lack of motivation. It’s easy to chalk it up to stress, a busy schedule, or “just getting older.” But sometimes these shifts aren’t simply about life circumstances. They may be connected to testosterone levels.

How Low Testosterone Shows Up

Testosterone plays a role in far more than strength or libido. When levels drop, the effects often show up in the way men feel day to day. Common signs include:

  • Persistent fatigue or lack of stamina

  • Irritability or a short temper

  • Depressed or flat mood

  • Loss of motivation or drive

  • Difficulty concentrating or brain fog

  • Less interest in intimacy

Because these symptoms overlap with depression and anxiety, many men are started on SSRIs or other psychiatric medications without having their hormones checked.

Why Mood and Hormones Are Connected

Testosterone directly influences brain chemistry. It supports neurotransmitters like dopamine and serotonin, which are tied to motivation, focus, and emotional balance.

When testosterone is low, men may experience:

  • Blunted emotions

  • More frequent mood swings

  • A sense of “not feeling like myself”

Addressing testosterone levels can bring clarity to whether mood changes are rooted in mental health alone, hormone imbalance, or a mix of both.

The Benefits of TRT for Mood

Research shows that restoring testosterone can improve mood, confidence, and quality of life. Many men describe it as lifting a fog they didn’t realize was there.

Benefits of TRT may include:

  • Improved energy and stamina

  • Better mood stability

  • Renewed motivation and focus

  • Greater response to therapy, counseling, or lifestyle changes

  • Increased sense of well-being

What to Consider Before Starting TRT

Testosterone therapy isn’t a quick fix — and it isn’t right for everyone. A thorough evaluation is essential. That means looking at:

  • Lab testing: total testosterone, free testosterone, SHBG, estradiol

  • Symptoms: how mood, energy, and libido are affecting daily life

  • Lifestyle factors: sleep, stress, exercise, and nutrition

TRT is safest and most effective when it’s tailored to the individual and combined with healthy lifestyle support.

My Approach

As both a hormone specialist and a psychiatric mental health nurse practitioner, I bring a dual perspective. I don’t separate mood from hormones — I connect them.

This approach means:

  • Fewer delays in finding the right treatment

  • Less trial-and-error with psychiatric medications alone

  • A plan that addresses root causes, not just symptoms

At The Listening NP, I take time to hear your story and help uncover what’s really going on. Schedule a Consultation and let’s start finding answers together.

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